Interactions between humans and mammals are a defining experience of human life. Humans have utilized mammals and their products for thousands of years. The spread of new inhabited places, accompanying facilities, and residential areas, which vary greatly depending on the species' original habitat, has destroyed large ecosystems. Mammals are used for various reasons including food, and medicine. Urbanization, industrialization, and hunting have damaged the mammalian landscape. These activities are the primary causes of mammal’s extinction. Mammals have adapted to new habitats and diets, but some species have failed to adopt, and they are rapidly declining. However, in an increasingly urbanized and resource-constrained world, we need to learn how to manage the risks from wildlife in new ways, and to understand how to maximize the diverse benefits that living with wildlife can bring. Ethnomammalogy is the study of human knowledge of mammals and this field of research helps with mammalian conservation efforts. Habitat loss is a global issue that has got a lot of attention in the last two decades. Human actions have had a significant impact on the chemical, biological and physical structure of the Earth's land and water. Keywords: Mammals, Ethnomammalogy, Food, Habitat loss, Human action.